Crosslinking Reagents
Cayman Chemical Sulfo-CynIn 5 5 1mg
An amine-reactive fluorescent probe; reacts with amine groups to form conjugates with peptides and proteins for detection by various fluorescent-based applications; has been used in cancer-targeted nanovesicles encapsulating perfluorooctyl bromide (PFOB) to identify their localization in mice; ex/em = 675/694 nm, respectively
Medchemexpress LLC BS3 crosslinker (disodium) | 127634-19-9 | not stated | 98.0% | 572.43 g/mol | C16H18N2Na2O14S2 | 50 MG
BS3 Crosslinker disodium is a water-soluble, non-cleavable homobifunctional amine crosslinker used for bioconjugation and antibody-drug conjugate synthesis. It contains sulfosuccinimidyl reactive esters that selectively react with primary amines to form stable amide bonds, enabling protein crosslinking and labeling under aqueous conditions. The reagent is supplied as a solid of high purity and requires sealed storage away from moisture and light; in solution, long-term storage at -80°C is recommended.
eMolecules 79642-50-5 | DSG Crosslinker | TargetMol | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 726061665
DSG Crosslinker | TargetMol | 79642-50-5 | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 726061665
eMolecules 79642-50-5 | DSG Crosslinker | TargetMol | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 10mg | 726061662
DSG Crosslinker | TargetMol | 79642-50-5 | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 10mg | 726061662
Kyfora Bio TriEGDA 25g
TriEGDA is a crosslinking monomer Crosslinking polymeric materials can be used to synthesize hydrogels which are suitable carriers for controlled drug delivery
Broadpharm Formula: C25H22N2O5Purity: 95%Storage Condition: -20 degrees Celsius
Formula: C25H22N2O5Purity: 95%Storage Condition: -20 degrees Celsius
Medchemexpress LLC Sulfo-SMCC sodium | 92921-24-9 | 99.9% | 500 MG
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker. It contains N-hydroxysuccinimide (NHS) ester and maleimide groups, which allow it to react with primary amines and sulfhydryl groups, respectively. This product is intended for research use only and is not sold to patients.
- Hetero-bifunctional
- Noncleavable ADC crosslinker
- Bears N-hydroxysuccinimide (NHS) ester group
- Bears maleimide group
- Reacts with primary amines and sulfhydryl groups
Medchemexpress LLC SPDP-PEG4-NHS ester | 1334177-95-5 | 95.0% | 50 MG
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules operate by utilizing the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. PROTACs consist of two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets the specific protein of interest.
- For research use only.
- Store pure form at -20°C for up to 3 years.
- Store in solvent at -80°C for up to 6 months, or at -20°C for up to 1 month.
- If stored at -80°C, stock solutions should be used within 6 months.
- If stored at -20°C, stock solutions should be used within 1 month.
eMolecules 79642-50-5 | DSG Crosslinker | TargetMol | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 50mg | 726061664
DSG Crosslinker | TargetMol | 79642-50-5 | MFCD00153597 | 326.261 | C13H14N2O8 | 0.000 | O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 50mg | 726061664
Medchemexpress LLC Sulfo-Cy5-N3 | 1481447-40-8 | 99.1% | 724.89 g/mol | C35H44N6O7S2 | 10 MG
Sulfo-Cy5-N3 is a red fluorescent azide reagent used for click-chemistry labeling of biomolecules and fluorescence imaging. It reacts via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and can also undergo strain-promoted azide-alkyne cycloaddition (SPAAC), enabling efficient conjugation to alkyne-bearing targets for detection and imaging applications.
- Red fluorescent azide reagent with excitation/emission ≈ 642/670 nm.
- Reacts in CuAAC and strain-promoted click chemistries for flexible labeling.
- High purity (99.12%) suitable for sensitive imaging assays.
- Available in small milligram quantities for research workflows.
- Solid form stable at -20°C; protect from light to preserve performance.
Medchemexpress LLC 1,2-distearoyl-rac-glycero-3-methylpolyoxyethylene | 308805-39-2 | 100.0% | 2000 (average) | C42H82O6 | 25 MG
DSG-PEG (MW 2000) is a methoxy-terminated PEGylated lipid used to incorporate polyethylene glycol chains into lipid bilayers. It is commonly used in liposome and lipid nanoparticle formulations to provide steric stabilization and extend circulation time. The material is supplied as a solid suitable for laboratory formulation and storage.
- Average molecular weight 2000 for PEG chain
- High purity (99.97%) suitable for formulation work
- Provides steric stabilization when incorporated into liposomes
- White to off-white solid, convenient powder form
- Recommended storage: powder at -20°C (long term) or 4°C (short term)
Medchemexpress LLC Dbco-sulfo-link-biotin | 1363444-70-5 | 653.77 g·mol⁻¹ | C31H35N5O7S2 | 1 MG
DBCO-Sulfo-Link-biotin is a water-soluble, cleavable click-chemistry linker that combines a dibenzocyclooctyne (DBCO) reactive group with a biotin affinity tag. It enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) for labeling azide-containing biomolecules and is used in biotinylation, protein labeling, and antibody-drug conjugate linker synthesis.
- Enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC).
- Provides a biotin tag for affinity capture and detection.
- Sulfo linker increases water solubility for aqueous bioconjugation.
- Suitable for biotinylation, protein labeling, and ADC linker incorporation.
Medchemexpress LLC Propargyl-C2-NHS ester | 906564-59-8 | 97.0% | 209.20 g/mol | C10H11NO4 | 500 MG
Propargyl-C2-NHS ester is a non-cleavable linker and click-chemistry reagent used for antibody-drug conjugation and general bioconjugation. It features an alkyne (propargyl) moiety for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and an N-hydroxysuccinimide (NHS) ester for efficient amine coupling.
- Molecular formula: C10H11NO4
- Molecular weight: 209.20 g/mol
- Purity: 97.0%
- Physical form: Colorless to off-white, solid/liquid mixture
- Solubility: 100 mg/mL in DMSO
- Storage: pure form -20°C (3 years); in solvent -80°C (6 months)
- Applications: antibody-drug conjugation and general bioconjugation